Research Opportunities Database
Associate Professor of Surgery (Research)
Phone: +1 401 444 8683
Location:Phone: 444 8683
Research SummaryRole of CR3 as a Pattern Recognition Receptor --
Neutrophils bind to ß-glucan which is a cell wall component of infectious microorganisms including fungi. Since glucan does not occur in mammals, ß-glucan provides a recognition system for the immune system to distinguish a pathogen from self.
Chemotaxis: How Migrating Neutrophils Acquire a Sense of Direction --
To determine how beta-glucan increases the directional movement of human neutrophils.