Research Opportunities Database
Assistant Professor of Medicine (Research)
Phone: +1 401 444 8654
Research SummaryThe role of p53 in alcoholic (ALD) and non-alcoholic (obesity-associated) fatty liver disease (NAFLD).
Both diseases are characterized by hepatocellular apoptosis, oxidative stress, insulin resistance and steatosis (excess fat accumulation).
Past or Present Projects Available:PAST
1. The p53 inhibitor, pifithrin-alpha p-nitro attenuates non-alcoholic fatty liver disease in mice
1. Pifithrin-alpha p-nitro reduces liver injury and steatosis in chronically ethanol-fed rats
2. The role of p53 in cellular fatty acid metabolism and insulin signaling