Research Opportunities Database

Stephen Gregory

Stephen Gregory

Associate Professor of Medicine (Research)

Department: Medicine

Phone: +1 401 444 7369

Email: Stephen_Gregory@Brown.EDU

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Location:

401-444-7369; sgregory@lifespan.org

Research Summary

Conducting experiments to determine the factors that facilitate protective immunity to pneumonic tularemia using laser capture microdissection (LCM) to isolate relevant immune cell populations from the lungs of immune and non-immune mice infected with F. tularensis, and DNA microarray and real-time RT-PCR analyses to characterize gene expression.

Past or Present Projects Available:

Listeria monocytogenes activation of NKT cell in the immune system; NKT cells suppress neutrophil inflammatory response in Listeria infection; Immune functions of the liver--antimicrobial activity of hepatocytes in the listeria model; Kupffer cells influence the biological response of inflammatory macrophages to LLO L. monocytogenes infection; Characterizing Mononuclear Phagocyte Populations during Listeria Monocytogenes Infection