Research Opportunities Database

Steven Moss

Steven Moss

Professor of Medicine

Department: Medicine

Phone: +1 401 444 6713

Email: Steven_Moss@Brown.EDU

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Location:

RI Hospital, 593 Eddy St, APC 414, Prov., RI - 444-6713

Research Summary

Current focus is on the effects of H. pylori in modulating gastric epithelial cell cycle control, via decreasing the expression of gastric p27(kip1), an important cell cycle regulatory and tumor suppressor protein.

Past or Present Projects Available:

Trefoil-binding proteins, Helicobacter pylori and gastric cancer; p27-binding partners in Helicobacter pylori-infected gastric cells; Immunopathogenesis of Helicobacter pylori infection in p27-deficient mice; Helicobacter pylori and gastric carcinogenesis; The role of p27 in murine models of hepatitis; Claudin expression in gastric cancer; Evaluation of Novel H. pylori Vaccine Epiitopes in Human Lymphocytes; Role of the gastrokine gene family in H. pylori-induced gastric cancer