Research Opportunities Database

Anita L. Zimmerman

Anita L. Zimmerman

Professor and Vice Chair

Department: Molecular Pharmacology, Physiology & Biotechnology

Phone: +1 401 863 2224

Email: Anita_Zimmerman@Brown.EDU

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Location:

BMC, Room 327

Research Summary

Molecular mechanisms of ion channel function and visual transduction; potential therapeutic agents for retinal degenerative diseases.

Past or Present Projects Available:

Targeting rod ion channels in the treatment of retinal degenerative diseases; Ion channels in retinal rod cells; Cloning and modulation of cGMP channels; Mutagenesis of cyclic nucleotide gated ion channels to study modulation by Ca++/Calmodulin; Insights on the molecular mechanisms of gating and inhibition of cyclic nucleotide-gated ion channels; Molecular mechanism of regulation of cylic nucleotide-gated ion channels by diacylglycerol; Structure-function studies of a region involved in the opening of a cyclic nucleotide-gated ion channel; Proteomic and Biochemical Analysis of Cav2.2 Ubiquitination