Research Opportunities Database

David Mills

Assistant Professor of Medicine (Research)

Department: Medicine

Phone: +1 401 444 5416

Email: David_Mills@Brown.edu

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Location:

Phone: 444-5010

Research Summary

The role of hepatic progenitor cells (oval cells in rodents) in liver carcinogenesis; Involvement of stem-like cells in models of spontaneous transformation

Past or Present Projects Available:

Investigation into Necl-5 microvesicle suppression of hepatic NK cytoxic killing; Comparison of microvesicle shedding between normal and transformed prostate epithelial cells; Suppression of natural killer cytotoxity by shed Necl-5 positive microvesicles; Accumulation of neoplastic traits following spontaneous in vitro transformation of rat prostate cell lines; The Effect of Microvesicles on Breast Cancer Cell-specific Phenotypic Changes; Transformed liver epithelial cell-derived microvesicles stimulate ND cytotoxicity